Continuous gas/liquid–liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination

نویسندگان

  • Jessica R Breen
  • Graham Sandford
  • Dmitrii S Yufit
  • Judith A K Howard
  • Jonathan Fray
  • Bhairavi Patel
چکیده

4-Fluoropyrazole systems may be prepared by a single, sequential telescoped two-step continuous gas/liquid-liquid/liquid flow process from diketone, fluorine gas and hydrazine starting materials.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Liquid Fuel Production from Synthesis Gas via Fermentation Process in a Continuous Tank Bioreactor (CSTBR) Using Clostridium ljungdahlii

The potential bioconversion of synthesis gas (syngas) to fuels and chemicals by microbial cell has attracted considerable attention in past decade. The feasibility of enhancing syngas bioconversion to ethanol and acetate using Clostridium ljungdahlii in a continuous tank bioreactor (CSTBR), kinetics and mass transfer coefficient of carbon monoxide (CO) utilization were evaluated. Two different ...

متن کامل

The green synthesis of pyrano[3,2-c]quinoline-2,5-dione derivatives catalyzed by acidic ionic liquid under ultrasound irradiation

Abstract-A novel and efficient method has been developed for the synthesis of pyrano[3,2-c]quinoline-2,5-dione derivatives by the convenient ultrasound-mediated condensation of 4-hydroxyquinolin-2-one with Meldrum’s acid and aldehydes in the presence of a catalytic amount of [HMIm]HSO4 as a green, efficient and reusable acidic ionic liquid medium. The stability of the ionic liquid during the re...

متن کامل

Brønsted acidic ionic liquid ([BMIm]HSO4) as an efficient catalysts for the one-pot synthesis of 2H-indazolo[2,1-b]phthalazine-trione derivatives

The Brønsted acidic ionic liquid ([BMIm]HSO4) catalyzed three-component synthesis of 2H-indazolo[2,1-b]phthalazine-trione derivatives at room temperature. The integrity of the ionic liquid remains reasonably unchanged when it is separated from the reaction mixture by water extraction, as it can be recycled several times without any loss of activity in each of the title syntheses. The products a...

متن کامل

Facile synthesis of dihydropyrimidinone derivatives via Biginelli reaction using Brønsted acidic ionic liquid [H-NMP]+[CH3SO3]- as an efficient homogeneous catalyst

In this research, a green, operationally simple, highly efficient and facile cascade Biginelli reaction using various aromatic aldehydes, ethyl acetoacetate, and urea/thiourea has been developed. First, the ionic liquid was prepared from the reaction of 1-methyl-2-pyrolidone with methane sulfonic acid. Then, this ionic liquid was applied as an acidic catalyst in the synthesis of dihydropyrimidi...

متن کامل

Facile synthesis of dihydropyrimidinone derivatives via Biginelli reaction using Brønsted acidic ionic liquid [H-NMP]+[CH3SO3]- as an efficient homogeneous catalyst

In this research, a green, operationally simple, highly efficient and facile cascade Biginelli reaction using various aromatic aldehydes, ethyl acetoacetate, and urea/thiourea has been developed. First, the ionic liquid was prepared from the reaction of 1-methyl-2-pyrolidone with methane sulfonic acid. Then, this ionic liquid was applied as an acidic catalyst in the synthesis of dihydropyrimidi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 7  شماره 

صفحات  -

تاریخ انتشار 2011